Acomplia (Rimonabant 20 mg)
Acomplia is one of the commercial names for the active agent Rimonabant which is used for weight loss in obesity. The medication suppresses the appetite and carving for delicious food by inhibiting cannabinoid receptors responsible for that which are especially active in people with bad food habits developed over years. The medication can help you significantly lose weight but has a number of contraindications and precautions for use. Find out more about Acomplia safe use from our guide.
What is the drug named Acomplia?
Acomplia is the brand under which the active substance Rimonabant is sold. The medication is available under different names because its formula isn’t longer protected by the know-how and can be replicated by different manufacturers. The medication is a cannabinoid receptor agonist that suppresses appetite and promotes weight loss when it is needed for medical reasons.
If you want to lose weight with the help of medications, you need to discuss this possibility with your doctor before you buy Acomplia. But note that in some countries the medication isn’t approved so your doctor may be not aware of the medication mechanism of action and its safety. Nevertheless, if you still want to use the drug, you should at least check that you don’t have any contraindications for its use and use it carefully.
When can you use Acomplia?
The medication is indicated for the loss of weight only in people with severely increased body mass with the body mass index over 30 or 27 but accompanied by diabetes type 2 or dyslipidemia (elevated amount of lipids in the blood).
The medication must not be used if you don’t suffer from obesity.
Please remember that even if you decide to use the medication to help yourself lose weight, you still need to put an effort in this process by changing your diet and doing at least some easy physical exercise. The weight loss occurs in the calorie deficit, i.e. when you consume fewer calories than you burn. Even simple walking can make you lose the extra calories that you consume. Do not try to reduce your food consumption drastically, lower the amount of the calories you consume today by 500-800 depending on your daily calorie intake so this number won’t be more than 30% of your consumed calories per day. It is a safe rate for weight loss which can be easily achieved with the use of today’s technology such as mobile apps for counting calories simply introducing the meals you eat in the app.
Advantages of Acomplia use
According to data provided by the World Association of Dietitians, the studies show that the weight of people with obesity in a year of the uninterrupted medication intake decreased by 5% or on average on 7 kilograms with the decrease of the waist by 9 cm. Even though it may seem not a large number, such weight loss can significantly improve the health of an individual who suffers from a severely increased body weight. The medication contributes to the lowered level of triglycerides and low-density lipoproteins. It also allows overcoming nicotine dependence and stopping smoking without accompanying weight gain. By stimulating the synthesis of adiponectin, Rimonabant significantly reduces the insulin resistance index and leads to the normalization of carbohydrate metabolism in patients with high glycemia on an empty stomach and with impaired glucose tolerance.
When consuming delicious, high-calorie and fat-rich food in the hypothalamus, the endocannabinoid system is hyper activated, which leads to an enhanced appetite and increased fat formation, and the energy saturation and expenditure lower accordingly. Fatty foods increase the availability of polyunsaturated fatty acids for the biosynthesis of endocannabinoids, which also leads to the hyperactivity of the endocannabinoid system.
In people who are diagnosed with obesity, the endocannabinoid system becomes especially active. It lies on the basis of food behavior, acting at the level of the central nervous system, and induces fat deposition, acting at the level of adipocytes.
The endocannabinoid receptors type-1 were discovered in 1990. These are the receptors affected by Acomplia which suppresses their sensitivity to tasty food. These receptors are present in the brain, gastrointestinal tract, in the myocardium, the vascular endothelium, and the sympathetic nerve endings.
In general, in the medication use, the main weight loss occurs within the first months of the therapy but the effect of the medication in the maintenance of the achieved weight loss is preserved within two years if the drug is used within this time.
Affecting them, the drug lowers the appetite and the process of fat storing. But before you buy Generic Acomplia, please read about its side effects, contraindications, and precautions.
What are possible negative effects of Acomplia use?
The possible adverse effects caused by the use of the medication are nausea, diarrhea, indigestion, dizziness, sleeplessness, anxiety, and depression with suicidal tendencies. Namely due to the last adverse effect, the medication is not widely used although the most popular and approved antidepressants also have a likelihood of this negative effect development.
However, if you decide to buy Rimonabant and use it continuously, it would be wiser to make sure that you don’t suffer from any mental health problems before you start taking the pills and pay close attention to the mood swings if they occur during the medication use and even stop the medication use immediately if you notice any negative thoughts or intentions while taking the pills. Considering that it might not be as obvious for you as for your family members, it is also advised to inform them about your therapy and ask them to tell you if they notice any changes in your behavior so that you could discontinue using the medication timely if any negative effects start to develop.
When is Acomplia use contraindicated?
You must not buy Generic Rimonabant and use it If you suffer from liver or kidney dysfunction of the severe stage, have increased sensitivity to the drug (if you have used it and suffered from adverse effects), suffer from depression or other mental disorder, are pregnant or breastfeeding. Besides, you must not give the medication to children.
With what other medicines the use of Acomplia must not be combined?
The medication must not be used with antidepressants as it is at all contraindicated for the use in people with the unstable psyche.
Rimonabant must not be combined with other medicines used for weight loss.
The medication is metabolized with the participation of CYP3A enzyme. Therefore, its effect and plasma concentration is influenced by the inductors and inhibitors of CYP3A such as ketoconazole, itraconazole, ritonavir, telithromycin, clarithromycin, nefazodone, and others.
If you take any other medications, it would be wise to refrain from taking Generic Acomplia in general because the drug itself has a number of possible side effects which can be enhanced by the use of other medicines.
How to use Generic Acomplia?
If the drug is not contraindicated to you, you can order Acomplia and use it by one 20 mg pill in the morning before breakfast.
Remember that the best results are achieved in a combination of the therapy with low-calorie diet and at least moderate exercises.
If you start suffering from any adverse effects or your family or friends notice that your behavior changed, stop using the pills immediately. Otherwise, the medication can be taken for two years without interruption.