Atacand (Candesartan 8 mg)
€39.80 – €124.20
Atacand and Generic Atacand are identical medications based on the active substance Candesartan, an angiotensin II receptor antagonist. The medications are used to treat hypertension and congestive heart failure if angiotensin-converting-enzyme inhibitors are ineffective or unsuitable. They can be used even in children older than one year. The dosages are adjusted individually but you can find out the generally recommended dosages from the medication guide below. The drug is sometimes combined with other blood pressure medications and diuretics but is incompatible with some other drugs. To be sure that in your case the medication is suitable, make sure to inform your doctor about all of your conditions and drugs that you take or plan to take.
Brand name: Atacand
Generic name: Candesartan
Indications: Arterial hypertension, High blood pressure, Congestive heart failure
Analogs: Candelong, Candisar, Spectra, Blopress
Generic Atacand (Candesartan 8 mg) guide:
Generic Atacand (Candesartan) is a medication used for elevated blood pressure lowering. It belongs to the class of angiotensin 2 receptor antagonist. The drug also shows benefits in the reduction of mortality in congestive heart failure.
When should the generic Atacand be used?
You can buy Generic Atacand (Candesartan) and use it as prescribed by your doctor or as said in the instruction if you suffer from hypertension, congestive heart failure, or disturbance of systolic function of the left ventricle (as an additional therapy to angiotensin-converting-enzyme inhibitors or in case of intolerance of angiotensin-converting-enzyme inhibitors).
What is the mechanism of action of Atacand (generic Candesartan)?
The active substance of Atacand, Candesartan, is a selective non-peptidic blocker of AT1-receptors of angiotensin II. It prevents the development of effects caused by angiotensin II. It dilates (widens) blood vessels and arteries, contributes to the decrease in the overall peripheral resistance of the blood vessels, promotes an increase in glomerular filtration rate and renal blood flow, as well as an increase in plasma renin activity and angiotensin I and angiotensin II concentrations.
Unlike angiotensin-converting enzyme inhibitors, the drug does not affect the metabolism of bradykinin (a peptide that causes blood vessels extension) and other peptide compounds, which explains its better tolerability. Due to a decrease in the total peripheral resistance and a decrease in blood pressure, the drug somewhat reduces the load on the myocardium.
The blood lowering effect is achieved within 60 minutes after the pill intake and is maintained within 24 hours.
The drug is transformed into an active form into the intestinal mucosa. The maximum concentrations in the blood plasma are observed within 3-4 hours after the drug intake.
The effectiveness of the drug is not influenced by food. The drug is excreted with feces
First of all, it’s worth noting that medication comes in different forms. The standard form is simple Atacand but there is an enhanced formula called Atacand HCT which is a combination drug in which the active substance Candesartan is accompanied with the diuretic drug hydrochlorothiazide. The dosages of the medications vary. Therefore, you have to clarify with your doctor what form of the medication you need before you buy Generic Atacand (Candesartan).
The generally recommended dosages are the following:
– Hypertension treatment in adults: the staring daily dosage is 16 mg taken orally once a day. Further and adjustment can be made and the maintenance dosage from 8 to 32 mg a day orally in divided doses can be used. The maximum dosage of Atacand or Generic Atacand for adults with normal kidney function is 32 mg a day.
The accumulated blood pressure lowering effect is usually observed within 2 weeks of the therapy after which your doctor can decide whether you need to lower the dosage, increase it or stick to the initial one.
– Congestive heart failure in adults: the starting dosage is 4 mg of the drug taken orally once a day. The dosage can be doubled after 2 weeks of intake if the desirable effect is not achieved and the drug is well tolerated. The optimal daily dosage is 32 mg in one intake but the adjustments to reach this dosage should be made not sooner than every 2 weeks.
– Hypertension treatment in children: for children from 1 to 6 years of age, the starting dosage should be 0.2 mg per kilogram of the body weight taken orally in one or two intakes. The standard therapeutic dosage is 0.05 to 0.4 mg per kilogram of the body weight taken in one or two intakes.
For children older than 6 years and younger than 17 years who weight less than 50 kg, the starting therapeutic dosage is from 4 to 8 mg a day taken orally in a single or two intakes. Further the dosage can be adjusted in the range from 2 to 16 mg a day taken in one or two intakes.
For the children from 6 to 17 years who weight 50 kilograms or more, the starting dosage is from 8 to 16 mg taken in one or two intakes a day. Later the dosage can be either lowered to 4 mg a day or increased up to 32 mg a day in one or two intakes. The dosage adjustments are made by the doctor based on the assessment of the patient’s tolerance of the drug and the effect achieved.
The dosages for people who suffer from stenosis of the renal artery, stenosis of the aortic and mitral valve, as well as primary hyperaldosteronism, and diabetes mellitus are chosen individually. Also, those people who underwent renal transplantation must use the drug only under a doctor’s supervision.
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