Generic Hepcvir (Sofosbuvir 400 mg) guide:
What is the drug marketed as Generic Hepcvir?
If you know the medication called Hepcvir, probably you or some of your family members were diagnosed with hepatitis C as Hepcvir is the trade name of the most innovative, effective, and safe medication for the therapy of this viral infection and the liver damage associated with it. The medication is based on the active antiviral agent called Sofosbuvir which was first approved and used in 2013. However, it is not the only medication based on the substance. The formula and ingredients have become available for the other drug makers pretty soon after the active agent discovery because the medication received a breakthrough status and the owner of the patent was obliged to share the formula of the medication with other producers in order to cover the demand for the medication around the world and more importantly to make the expensive drug more affordable for people from the developed and underdeveloped countries where the virus of hepatitis C is most widespread.
The 12 to 24 weeks treatment course cost to date in the U.S. with the branded medication goes up to a hundred dollars while the treatment course with the medication known as Generic Hepcinat or Generic Sofosbuvir is only around $3,000-$4,000 depending on the manufacturer and the seller’s margin. This difference in prices is caused by the production costs and margins the manufacturers set in order to get profit from the medicines selling. In fact, Generic Hepcvir is basically Hepcvir or Sovaldi simply made by another company. Although, Generic Hepcvir is not an official name of the medication but rather a commonly accepted term used by doctors, pharmacists, and patients to prescribe or buy cheaper analogs of the expensive branded medicine. All of the generics have their own trade names registered but it would be hard to remember them all so you can simply look for a way to buy Generic Hepcvir when your doctor prescribes you Sovaldi, Hepcvir, or Sofosbuvir.
Does generic provide the same effect?
Yes. The cheaper price of the generic doesn’t indicate its lower quality of lower effectiveness. The preparation is made using absolutely identical formula and ingredients. However, in order to be sure that you do not purchase a counterfeit medication, you should opt for a reputable seller such as our online drugstore.
When to use the preparation?
The only indication for the medication use is diagnosed hepatitis C. However, in some cases the even in the confirmed diagnosis of the disease the drug cannot be used if a patient has contraindications for use (read below).
Hepatitis C is a very dangerous and insidious disease that attacks the liver. It can hide behind the untypical symptoms and be discovered when significant and irreversible damage to the liver is already done. Therefore, if you had any contact with people with hepatitis C such as, for instance, offered any medical or hygienic service to the carrier or had intimacy with the individual affected by the illness, you must take blood tests for the presence of the virus.
Currently, nearly 150 million of people around the world are diagnosed with the disease. They are all in danger of the development of liver cirrhosis and liver cancer. From these complications of the viral infection, around 350,000 of people around the world die yearly. The most dangerous carriers of the disease are people with chronic hepatitis C who can infect their sexual partners, children, medical workers, including dentists and nurses, who render medical services to them.
To date, 7 genotypes of the virus are known. They are all treated with the same medications but require different schemes of the therapy.
Worth noting that even if the drug isn’t contraindicated for you, it’s not enough to buy Hepcvir and start the therapy. In most cases, depending on the factors, doctors prescribe a combination of antiviral medicines and supporting therapy based on the general health condition and condition of the liver. Therefore, we advise you to get a precise diagnosis and ask your doctor whether this medication is suitable for you if your doctor hadn’t recommended the drug to you, clarify whether you need to receive a combination therapy, get instruction on the treatment scheme and only then purchase the preparation and start using it.
For whom Generic Hepcvir is contraindicated?
The preparation is contraindicated to be used in allergy or hypersensitivity to the components of the pills, for people younger than 18 years of age, in severe renal failure (creatinine clearance < 30 ml per minute).
Precautions and limitations
The effectiveness and safety of the drug is unknown in patients who have both hepatitis B and C, people who have the virus of the 1,4,5 or 6 genotype and were irresponsive to the previous therapy as well as developed liver cirrhosis or other serious condition of the liver.
The medication is not advised to be combined with telaprevir or boceprevir. Therefore, you need to consult your health care provider whether you can buy Sofosbuvir instead or continue the started therapy.
How the medication should be used?
Although here in this medication guide we provide the instructions on the drug use available in the official instruction, we strongly advise you to clarify the dosage regimen and treatment scheme with your doctor.
The preparation is taken in the dose of a single 400 mg pill a day with meal at the same time every day.
The schemes depend on the virus genotypes:
– Genotype 1 requires the use of Hepcvir or its generic with Ledipasvir for 8-12 weeks. Alternatively, a therapy with Hepcvir plus Daclatasvir can be done for 12 weeks.
– Genotype 2 requires the use of combination of Hepcvir with Ribavirin or Daclatasvir for 12 weeks.
– Genotype 3 requires the use of combination of Hepcvir with Ribavirin for 24 weeks. Alternatively, the drug can be used along with Daclatasvir for 12 weeks.
– Genotype 4 requires the use of combination of Hepcvir with Ledipasvir or Daclatasvir for 12 weeks.
The alternative regimens are provided in the original instruction for the therapy of hepatitis C in patients with HIV or compensated liver cirrhosis:
– Genotype 1 in the above-mentioned groups of patients requires the use of Hepcvir plus Ledipasvir for 24 weeks. Alternatively, the therapy can include the intake of the first two drugs and addition of Ribavirin. The therapy with the three drugs is made for 12 weeks. In both schemes, Ledipasvir can be replaced with Daclatasvir without the changes in the treatment course durations.
– Genotype 2 requires the use of Hepcvir/ Ribavirin for 16-20 weeks. Alternatively, instead of Ribavirin, Daclatasvir is used along with Hepcvir for 12 weeks in total.
– Genotype 3 requires the use of Hepcvir, Daclatasvir, and Ribavirin all at the same time for 24 weeks.
– Genotype 4 requires the use of Hepcvir / Ledipasvir for 24 weeks. If Ribavirin is added to the scheme, the treatment is made for 12 weeks. Alternative option is Hepcvir plus Daclatasvir for 24 weeks or plus Ribavirin for 12 weeks.
Possible side effects
When you buy Generic Sofosbuvir, you should be prepared that you can start suffering from certain adverse reactions once you begin the therapy. The majority of side effects however are caused when the medication is used along with other antiviral medicines, but if the side effects are not life-threatening and are tolerable, you should continue the therapy because the effect of the combined therapy is much greater. The typical negative effects are headache, decreased appetite, loss of weight, chronic fatigue, insomnia, irritability, anxiety, depression, and others.
Even if the side effects are mild, you need to inform your doctor as he or she can decide that they are the signs of the developing life-threatening condition and that you need a new treatment plan.
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