Mevacor (Lovastatin 10 mg)
€46.10 – €116.10
Mevacor or Lovastatin is used for the treatment of the diseases in which the level of lipoproteins of low density is increased and cannot be sufficiently lowered with diet and other non-drug methods. The medication can be used in children and adolescents who hit a certain stage of puberty but only if a pediatrician approves. Find out how to use the medication, avoid any side effects development, and so on from our complete guide based on the FAQ.
Brand name: Mevacor
Generic name: Lovastatin
Indications: Dyslipidemia, High cholesterol, Prevention of cardiovascular diseases, Hypercholesterolemia, Combined hypercholesterolemia and hypertriglyceridemia, Lipid profile correction, Hyperlipoproteinemia, Atherosclerosis
Benefits: Helps to decrease the level of bad cholesterol and raise the level of good cholesterol
Analogs: Lostatin, Lovacard, Recol, Altocor, Closterol, Colevix, Hipovastin, Lovasterol, Mevastatin, Pravastatin, Rovacor, Sivlorv
Generic Mevacor (Lovastatin 10 mg) guide:
What is the medication marketed as Mevacor?
Mevacor is not an exclusive medication. It is simply a promoted trade name for the medication called Lovastatin that had been developed in the 1970s. The active substance Lovastatin is actually partially a natural substance found in a type oyster mushroom. When its cholesterol-lowering properties were discovered, the researchers started to work on the synthesizing of the medication and testing of its safety when used by people. After many years of research, the optimal formula was developed and the medication was first approved in 1982. Nowadays, the patent of the inventor had already expired which made it possible for other medication manufacturing companies to make the same drugs and market them but under different names.
Lovastatin is a hypolipidemic medication, i.e. it disrupts the early stages of the synthesis of cholesterol in the liver (in the stage of mevalonic acid). In the body, it forms a free beta-hydroxy acid, which competitively suppresses HMG-CoA reductase and breaks its transformation into mevalonate, as a result of which the synthesis of cholesterol decreases, its catabolism increases. The preparation reduces the concentration of low density and very low-density lipoproteins in the blood and moderately increases high-density cholesterol levels. Besides, it significantly reduces the amount of apoprotein B (included in the composition of low-density lipoprotein) and other circulating components of low-density cholesterol. The expressed therapeutic effect is manifested within 2 weeks, and the maximum effect can be observed within 4-6 weeks from the start of treatment.
When taken orally, the medication is slowly and incompletely absorbed from the digestive (about 30% of the dose taken). The intake on an empty stomach reduces absorption by 30%. The maximum concentration is reached after 2 hours, but then the level in the plasma rapidly decreases and after 24 hours it is 10% of the maximum. Both Lovastatin and its beta-hydroxy-acid metabolite in the common vascular bed circulate in plasma-related form (about 95%).
The stable equilibrium concentration of Lovastatin (and its active derivatives) when applied once a day at night (cholesterol is synthesized mainly at night) is achieved on the 2-3rd day of therapy and 1.5 times higher than due to a single dose. It penetrates the GEB and the placental barrier, accumulates in the liver, where it is oxidized to metabolites, some of which remain active. The preparation, in general, excreted in bile. About 85% of the dose is excreted in feces and only 10% with urine. The pronounced lipid-lowering effect develops in 2 weeks, the maximum – within 4-6 weeks.
You should buy Mevacor or a generic drug with the same composition if diet and exercising failed to lower the level of bad cholesterol in your body.
What is Generic Mevacor? Is its effect different from the branded medication’s effect?
The generic version of the medication, ideally, should be absolutely identical to the branded medication. However, it is not always so. To be sure that you get the right medication, first of all, you should buy Generic Mevacor from a reliable seller. For instance, our online pharmacy specializes in the selling of the best quality generics that are made by reputable generics makers whose medications are properly tested and certified before they are allowed onto the market. Secondly, when you get the generic version of the medication you should check the active substance that should correspond to the active substance of the branded medicine you are prescribed to take. In case of Mevacor, it must be Lovastatin. Basically, if you get the qualitative generic medication, there are only two things that differentiate it from the branded medicine – the name on the box of pills and the price per pill. The different name is due to the fact that other producers cannot use the copyrighted name but they can use the formula. The cheaper price is due to the lack of research, i.e. generic drug makers do not develop the medicines themselves. Besides, all branded medicines, especially marketed in the U.S., are highly overpriced. The generics make it possible for people from all social classes and those without insurance to receive the best, modern and effective treatment without going broke. The idea of their creation is to balance the chances for effective and modern treatment for all people regardless of their incomes. This policy was initially aimed at helping people from the developing countries but considering the high prices for the branded medicines, more and more people from the developed world also prefer generics these days.
When should I buy Mevacor?
It is recommended to start using the pills only after other measures such as diet, exercise, and weight loss have not improved the cholesterol level sufficiently. The medication is appointed for the following conditions: primary hypercholesterolemia with a high concentration of low-density lipoprotein type IIa and IIb (with ineffective diet therapy in patients at increased risk of coronary atherosclerosis), combined hypercholesterolemia and hypertriglyceridemia, lipid profile correction in patients with uncomplicated type 1 and 2 diabetes mellitus, hyperlipoproteinemia (not amenable to special diet and physical activity), and atherosclerosis.
Please do not buy Lovastatin before consulting your doctor even if you have any of the above-listed conditions. It is important for a specialist to assess your general condition taking into account other factors before choosing a medication for you.
When shouldn’t I buy Generic Mevacor?
The prohibitions for the medication use include hypersensitivity to the pills’ components, acute liver diseases, pregnancy and lactation, liver dysfunction, and the general bad condition of a patient. Besides, it must not be used in children.
If you buy Generic Lovastatin and suffer from the following conditions, you must use the medication cautiously and in case of any adverse effects discontinue the therapy: liver diseases (including in the past), alcoholism, organ transplantation, concomitant immunosuppressive therapy, chronic renal failure, and urgent surgical manipulations (including dental procedures).
Side effects Generic Lovastatin can cause
Generally, the drug is well tolerated. Adverse reactions, if they occur, usually proceed in a mild form and are short-lived. The possible side effects caused by the generic are the same as the negative effects caused by the branded drug. They include nausea, vomiting, loss of appetite, abdominal pain, constipation, diarrhea, indigestion, flatulence, dry mouth, taste change, sour regurgitation, pancreatitis, hepatitis, cholestatic jaundice, dizziness, headache, agitation, anxiety, depression, cognitive disorders, diabetes, and others.
If you start suffering from any malaise taking the pills, make sure to inform your doctor right away.
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