Pulmicort (Budesonide 100 mcg)
€49.10 – €214.10
Generic Pulmicort is the same medication as the branded drug but made by the pharmaceutical company Cipla. The inhaler sold at this web page is used as a basic therapy of asthma; in insufficient efficiency of beta 2-adrenostimulants to reduce the dose of oral glucocorticosteroids, and in chronic obstructive pulmonary disease. It can be used in adults and children older than five years of age.
Brand name: Pulmicort
Generic name: Budesonide
Indications: Asthma, Chronic obstructive pulmonary disease
Benefits: Helps to prevent the bronchospasm or acute asthma attacks and lower their severity
Analogs: Budez, Plumicort, Bidien, Cortivent, Desonide, Desowen, Entocort, Micronyl, Preferid, Rhinocort, Spirocort, Tridesilon
Generic Pulmicort (Budesonide 100 mcg) guide:
What is the medication marketed as Pulmicort?
Pulmicort is a brand name patented for the medication called Budesonide. The active agent of the medication is a glucocorticoid, i.e. a type of steroid hormone that reduces the inflammation, has anti-allergic, and immunosuppressive effects.
For the first time, the formula of the substance was patented in 1973. In 1981, it was first used for the therapy of asthma. Currently, as the patent of the formula developer expired, the same medication is produced by numerous pharmaceutical companies but is sold under different names.
The medication is available in different forms: as capsules for oral use, ointment for local application, nasal spray, vials for rinsing the nose, suppositories for bowel diseases, and the aerosol inhaler for asthma. On this web page, we offer you to buy Pulmicort in a generic version. Here in this section of our online pharmacy, you can buy anti-asthma medications that are also suitable for obstructive lung disease, chronic bronchitis, and emphysema. If you need Budesonide for other condition, please look for it in other sections or contact our pharmacists for an advice.
The inhaler has a prolonged effect and therefore can be used once daily. It is characterized by local anti-inflammatory action due to high lipophilicity (affinity for organic substances) and ability to penetrate intracellularly, bind to glucocorticoid receptors. The mechanism of action of Budesonide is built on the formation of complexes with the glucocorticoid receptors of the cytoplasm. These complexes made of hormones and receptors then penetrate the nuclei of target cells, bind to DNA and activate genes that are responsible for the production of lipocortin. Lipocortin is an inhibitor of phospholipase A2 – the enzyme, it inhibits the synthesis of mediators of inflammation: histamine, leukotrienes, and cytokines.
Besides, the medication also prevents the migration of inflammatory cells, elevates the number of active beta-adrenergic receptors, and restores the body’s response to beta-adrenergic bronchodilators after long-term use.
The drug is rapidly absorbed after inhalation. 34% of the dose is stored in the lungs. Absolute system availability is 39% of the received dose. The maximum concentration of Budesonide in the blood plasma is reached 30 minutes after inhalation. The amount of distribution is approximately 2-3 l per kilogram of the body weight. Metabolism of most of the preparation (about 90%) occurs in the liver with the action of the CYP3A4 enzyme with the production of metabolites with low glucocorticosteroid activity. Nearly 90% of the dose goes into an inactive state already during the first passage through the liver. Metabolism in the lungs is insignificant. In adults, the half-life of the preparation is on average two hours, in children it is one and a half hours. The binding of the prepration to plasma proteins varies from 85 to 90%. The active substance is excreted in the urine (70%) and bile. Since the main action of the preparation occurs in the respiratory tract, there is no data on the relationship between plasma concentration and the potency of its action.
What is the medication sold as Generic Pulmicort?
Generic Pulmicort sold at this web page is identical to the branded medication in a form of aerosol. It is simply made by another pharmaceutical company, a well-known manufacturer Cipla. The generics are ideally all identical to the branded medicines but it is not always so. Only the reliable manufacturers are able to ensure that their products fully correspond to the original formula and effect of the branded drug. We sell only the best quality generics that had been thoroughly tested and approved for international selling.
Generic medications are able to be produced when the exclusive right of the developer for the production of the medication expires. This practice is approved and even promoted by the World Health Organization to ensure that people from all countries and social classes have access to the most effective and innovative medications. The cheaper price of the generic doesn’t indicate its lower quality. In fact, the high price of the branded medicine is unreasonable. Therefore, when you buy Generic Pulmicort you basically obtain the same medication but without overpaying for the advertised name.
2 inhalers, 3 inhalers, 4 inhalers, 5 inhalers, 10 inhalers