Generic Zerit (Stavudine 30 mg) guide:
What is Generic Zerit? Is it different from the branded medicine?
If your doctor prescribes you Zerit, you can without any doubts buy Generic Zerit instead from our online drugstore. The thing is that Zerit is nothing more than a brand name registered by a certain pharmaceutical company. The active substance used in the medication is called Stavudine. It was discovered in the 1960s and is currently manufactured under a variety of trade names. The active agent is used for the treatment of HIV and AIDS in combination with other medicines.
Stavudine is included in the list of Essential Medicines of the World Health Organization. Namely due to this reason the medication is currently available in a form of generics. The generics of the medication are identical to the branded medicine and are available all over the world at the lower prices than the branded medicine which is why more and more people prefer to buy Generic Stavudine instead of the widely-promoted drug. The medications known as generics are widely used in the developing and underdeveloped countries where the expensive branded drugs cannot be used. However, no generic enters the market if it doesn’t correspond to the original formula, quality, and effect. Therefore, there is no point of buying a branded medicine even if you live in the developed country where the expensive branded medicines are available.
Does the cheap price means that the medication is inferior?
No, the cheaper price of the generic isn’t caused by the poor quality. First of all, it is explained by the fact that the manufacturer didn’t’ invent the medicine but simply got the right to manufacture the preparation after the patent of the drug developer expired. Secondly, the generic drug makers do not advertise their medicines. Thirdly, they sell the medicines in certain countries or regions without going to the expensive markets where the approval of the medication and the competition forces pharmaceutical companies to set higher prices. Fourthly, the major makers of generics are operating in India, the country where the production of the medications is much cheaper than in the U.S. or in the Western Europe. Worth noting though that the large world known pharmaceutical brands also make their medications there as it is cheaper to outsources the labor force in the developing country.
When the medication should be bought?
Zerit or Stavudine is an antiviral medicine used for the prophylaxis and against the most dangerous retrovirus, human immunodeficiency virus (HIV) and the condition that can develop from the virus, acquired immunodeficiency syndrome (AIDS).
The prophylaxis of HIV is required if you had an unprotected sexual intercourse with a person with HIV or AIDS, have had any contact with the blood or any other bodily fluids of the infected person, and for medical workers who have cut or pierced their skin with a needle or instrument that contained blood or bodily fluids of an infected person.
The medication currently isn’t prescribed as a first-line therapy due to its high level of toxicity. It is also usually not used alone for the therapy. However, if a patient isn’t responsive to the more modern preparations with fewer side effects or simply cannot afford those medications, he or she is prescribed to start the therapy with Stavudine. Fortunately, today HIV and AIDS diagnoses are not equal to a death sentence. If you start the prophylaxis or the treatment timely, you can live a long and happy life without even worrying that your children or partner can get infected.
Who must not use the medication?
You should not buy Zerit or its analogs if you have previously used any medication with Stavudine in its composition and suffered from severe side effects. The medication is also contraindicated for people with severe liver dysfunction.
The drug is not recommended to be used during pregnancy but still can be prescribed if the expected good for the mother exceeds the potential harm to the fetus.
How the medication is used?
We assume that you buy Stavudine after your doctor prescribed you the medication. If you have the precise recommendations on how to take the medication from your doctor, follow these recommendations and neglect the instruction. Here we provide the information available in the label of the medicine but you must clarify with your doctor whether this treatment regimen is suitable for you.
The pills should be taken orally without chewing and be washed down with a sufficient amount of water (at least a half of a glass), preferably at least one hour before meal or with a light meal.
Adults with the body mass more than 60 kilograms are prescribed to take 40 mg two times a day. People with the body weight lower than 60 kilograms are prescribed to take 39 mg two times a day. The interval between the intakes should be 12 hours.
Children older than 6 years with the body mass not lower than 30 kilograms are prescribed 1 mg per kilogram, of the body weight 2 times a day. Children over 6 years of age with the body weight over 30 kilograms should take 30 mg 2 times a day. The interval between the intakes should be 12 hours.
If during the therapy develop the symptoms of neuropathy such as sensation of numbness, tingling, or pain in the feet, the treatment must be stopped. In the immediate cessation of the therapy, the symptoms usually fade away quickly.
Dosage adjustments in patients with renal dysfunction:
– In creatinine clearance more than 50 milliliters per minute, the dosage for people with the body mass over 60 kg is 40 mg taken every 12 hours, for people with the body mass lower than 60 kilograms the dosage is 30 mg every 12 hours.
– In creatinine clearance between 26-50 milliliters per minute, the recommended dosage for people with the body mass over 60 kg is 20 mg taken every 12 hours, for people with the body mass lower than 60 kilograms the dosage is 15 mg every 12 hours.
– In creatinine clearance between 26-50 milliliters per minute, the recommended dosage for people with the body mass over 60 kg is 20 mg taken every 24 hours, for people with the body mass lower than 60 kilograms the dosage is 15 mg every 24 hours.
Worth noting that for people with impaired kidney function other forms of the preparation are preferable.
The treatment course duration is established by a doctor.
What side effects can you expect from the medication use?
When you order Zerit, you should be prepared that the medication can cause certain serious adverse reactions: lactate-acidosis, lipoatrophy, and polyneuropathy.
The symptoms of these conditions can be mild and develop unnoticed. Therefore, you must undergo all tests recommended by your doctor during the therapy.
The other symptoms include the lowered sensitivity of the limbs, tingling sensation, muscle pain, headache, insomnia, dizziness, pain in the abdomen, pancreatitis, dryness in the mouth, loss of appetite, liver dysfunction, allergic reactions such as rash or fever, and so on.
If during the therapy you start suffering from the symptoms of neuropathy such as sensation of numbness, tingling, or pain in the feet, the treatment must be stopped. In the immediate stop of the therapy, the symptoms usually fade away quickly.
Interaction with other medicines
The medication is combined with other antiretroviral medications for the better suppression of HIV. However, it is incompatible with certain medications:
– It increases the toxic effect of zalcitabine and didanosine.
– The medication also must not be used with other preparations able to cause peripheral neurological disorders as the drug itself is able to cause them and in this combination the risk increases greatly.
Overdose with zerit
The symptoms of an overdose include general weakness, nausea, vomiting, and enhanced adverse reactions.
Treatment requires gastric lavage, intake of sorbents (for instance, activated carbon), and symptomatic therapy.
30 caps, 60 caps, 90 caps, 120 caps